I have been using this (and its big brother, the 1 day tactix pack) for EDC for a couple of years now (when I'm not using the Summit side satchel). One thing that sets the First Tactical packs apart is that the straps are adjustable, not just from the bottom, but from the top, too. This helps if you're slightly bigger than average: on most backpacks, you can't get the padding to quite the right place. But with the First Tactical packs, you can move it by lengthening the straps from the top as well as the bottom. It really does make for a more comfortable fit.
Other good points about this pack: the extra compartments on the front are really useful. This one has two slip pockets per side (the 1 day pack has 3).
The laptop compartment is accessible from outside, without opening the pack, and has a couple of slip pockets at the top that are useful for things like a phone.
The mesh bags that stick anywhere (via velcro) are really handy. You can see what's inside, and you can take them out of your bag if you want.
The organizer panel is pretty good.
It doesn't come with a waist strap, but it does come with the correct attachment points built in, so I just attached my own waist belt (just a piece of webbing + a buckle).
In general, I really like the fact that this has lots of attachment points everywhere: on the back, sides, straps. I've used many of them, sometimes in ways I'm pretty sure the original manufacturers never thought of.
One drawback to this pack is that it doesn't come with a water bottle pocket on the side. You can add one (I've done that), but when you do it doesn't sit quite as flush as if it were built in. But it works pretty well.
Another small negative: the upper outer compartment is fine but has no internal organization at all. That seems like a missed opportunity. It also doesn't have a bidirectional zipper pull.